Jess, a separated and nurse who moves with her daughter and young son Owen back into her old farmhouse. Shortly after settling in, Owen is bitten by the dog, resulting in a mysterious infection from the bite.
On Christmas Eve, 1899, Edward Newgate [Sturgess] arrives at the imposing gates of Stonehearst Mental Asylum, eager to be granted an apprenticeship with the superintendent. Delighted to share his knowledge and philosophy, Dr. Lamb [Kingsley] agrees and immediately takes Edward on a tour of the asylum, proudly introducing his staff and the troubled patients in his care, including the hauntingly beautiful Eliza Graves [Beckinsale] – a captivating woman whose violent aversion to intimacy has ensured her permanent residence at Stonehearst. As the days pass, Edward observes Lamb’s modern methods.
When veteran 911 operator, Jordan (Halle Berry), takes a life-altering call from a teenage girl (Abigail Breslin) who has just been abducted, she realizes that she must confront a killer from her past in order to save the girl's life. Directed by Brad Anderson, a director of thriller and horror films and television projects, he is best known for having directed The Machinist (2004), starring Christian Bale.