After his hands are injured in a car accident, an arrogant surgeon travels to the ends of the earth in search of healing, discovering the Ancient One and a world of sorcery and alternate dimensions.
A divorced and single parent, Eva (Julia Louis Dreyfus) spends her days enjoying work as a masseuse but dreading her daughter's impending departure for college. She meets Albert (James Gandolfini)—a sweet, funny and like-minded man also facing an empty nest. As their romance quickly blossoms, Eva befriends Marianne (Catherine Keener), her new massage client. Marianne is a beautiful poet who seems "almost perfect" except for one prominent quality: she rags on her ex-husband way too much.