Picking up immediately after the events in Resident Evil: Retribution, humanity is on its last legs in Washington D.C. As the only survivor of what was meant to be humanity's final stand against the undead hordes, Alice must return to where the nightmare began - Raccoon City, where the Umbrella Corporation is gathering its forces for a final strike against the only remaining survivors of the apocalypse. In a race against time Alice will join forces with old friends, and an unlikely ally, in an action packed battle with undead hordes and new mutant monsters.
In a world ravaged by a virus infection, turning its victims into the Undead, Alice (Milla Jovovich), continues on her journey to find survivors and lead them to safety. Her deadly battle with the Umbrella Corporation reaches new heights, but Alice gets some unexpected help from an old friend. A new lead that promises a safe haven from the Undead takes them to Los Angeles, but when they arrive the city is overrun by thousands of Undead - and Alice and her comrades are about to step into a deadly trap. The film is directed by Paul W.S.