After a colossal and mysterious accident a young talented architect comes back to his senses in a very odd world that only resembles the reality. This world is based on the memories of the ones who live in it - people who are currently finding themselves in a deep coma. Human memory is spotty, chaotic and unstable. The same is the COMA - odd collection of memories and recollections - cities, glaciers and rivers can all be found in one room. All the laws of physics can be broken.
Nerdy video game developer Miles (Daniel Radcliffe) is a little too fond of stirring things up on the internet with his caustic, prodding, and antagonizing comments. One night, he makes the mistake of drunkenly dropping an inflammatory barb on a broadcast of Skizm, an illegal death-match fight club streamed live to the public. In response, Riktor (Ned Dennehy), the maniacal mastermind behind the channel, decides to force Miles to join the "fun." Miles wakes to find heavy pistols bolted into his bones, and learns Nix (Samara Weaving), the trigger-happy star of Skizm, is his first opponent.